Leaders Unscripted – Microsoft South Africa CEO Vukani Mngxati explains why businesses can’t ignore the AI revolution
In this episode of Leaders Unscripted – an EY Transformative Podcast Series – Microsoft South Africa CEO Vukani Mngxati reflects on the scale of the AI revolution and its impact on businesses.
Mngxati stepped into the role of CEO of Microsoft South Africa in October 2025, bringing more than two decades of experience in technology, consulting, and strategic transformation. His leadership journey began in KwaZulu‑Natal and spans over 25 years of helping organisations modernise, innovate, and create impact at scale.
Before joining Microsoft, Mngxati spent 18 years at Accenture, where he led major digital transformation programmes across industries. He ultimately served as CEO of Accenture South Africa and Africa, steering the firm through significant shifts in technology, skills development, and economic change.
Beyond his corporate roles, he serves as a Board Member at Endeavor South Africa and Collective X, championing high‑impact entrepreneurship and the development of digital skills pathways for young people.
Today, as the leader of Microsoft South Africa, Mngxati is focused on advancing the country’s digital and AI transformation. His mission is centred on enabling inclusive economic growth, building critical digital capabilities, and ensuring that AI benefits businesses, communities, and future generations.
The interview
In this interview, Mngxati begins by explaining what makes AI different to previous tech disruptions – like the cloud and mobile – and why South African business leaders can’t afford to ignore this revolution.
He unpacks what separates organisations that are using AI to create value from those that are simply experimenting with AI.
Mngxati then suggests how boards and C-level executives should consider AI for their organisations, including how they can put guardrails in place to protect privacy and security without crippling innovation.
He also highlights AI use cases that made him stop and think, “this changes how business gets done.”
Finally, Mngxati suggests where he sees AI being used by organisations in the next few years and how leaders can prepare.
Watch the full Leaders Unscripted interview with Microsoft South Africa CEO Vukani Mngxati below.
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